Year to December 31, 2009
$'M
2008
$'M
CASH FLOWS FROM OPERATING ACTIVITIES:    
 
Net income 491.4 152.4
 
Adjustments to reconcile net income to net cash provided by operating activities:    
 
Loss from discontinued operations 12.4 17.6
 
Depreciation and amortization 250.2 202.9
 
Share-based compensation 65.7 65.2
 
IPR&D charge 1.6 128.1
 
Impairment of intangible assets - 97.1
 
Impairment of available-for-sale securities 0.8 58.0
 
Gain on sale of non-current investments (55.2) (10.1)
 
Gain on sale of product rights (6.3) (20.7)
 
Other 12.2 10.5
 
Movement in deferred taxes (98.8) 74.0
 
Equity in losses/(earnings) of equity-method investees 0.7 (2.4)
 
Changes in operating assets and liabilities:    
 
(Increase)/decrease in accounts receivable (212.3) 9.4
 
Increase in sales deduction accrual 134.7 84.3
 
(Increase)/decrease in inventory (38.7) 36.4
 
Decrease/(increase) in prepayments and other current assets (30.1) (9.6)
 
Decrease in other assets 0.8 3.6
 
Increase/(decrease) in accounts and notes payable and other liabilities 38.6 (99.0)
 
Returns on investment 4.9 7.1
 
Cash flows used in discontinued operations (5.9) (4.7)
 
 
Net cash provided by operating activities(A) 626.9 800.1
 
 
CASH FLOWS FROM INVESTING ACTIVITIES:    
 
Movements in restricted cash (3.9) 10.3
 
Purchases of subsidiary undertakings and businesses, net of cash acquired (83.3) (499.4)
 
Payment on settlement of TKT appraisal rights litigation - (419.9)
 
Purchases of non-current investments (0.9) (2.2)
 
Purchases of property, plant and equipment (254.4) (236.0)
 
Purchases of intangible assets (7.0) (25.0)
 
Proceeds from disposal of non-current investments 19.2 10.3
 
Proceeds from disposal of property, plant and equipment 1.0 1.8
 
Proceeds/deposits received on sales of product rights - 5.0
 
Proceeds from disposal of subsidiary undertakings 6.7 -
 
Returns from equity investments 0.2 0.6
 
 
Net cash used in investing activities(B) (322.4) (1,154.5)
 
 
CASH FLOWS FROM FINANCING ACTIVITIES:    
 
Proceeds from drawings under bank facility - 190.0
 
Repayment of drawings under bank facility - (190.0)
 
Proceeds from building finance obligation - 11.3
 
Payment under building financing obligation (4.7) (1.8)
 
Excess tax benefit of share-based compensation 16.8 -
 
Costs from issue of common stock, net - (5.6)
 
Proceeds from exercise of options 14.6 11.4
 
Payment of dividend (54.4) (46.8)
 
Payments to acquire shares by Employee Share Ownership Trust ('ESOT') (1.0) (146.6)
 
 
Net cash used in financing activities(C) (28.7) (178.1)
 
 
Effect of foreign exchange rate changes on cash and cash equivalents(D) 4.9 (11.8)
 
 
Net increase/(decrease) in cash and cash equivalents(A+B+C+D) 280.7 (544.3)
 
Cash and cash equivalents at beginning of period 218.2 762.5
 
 
Cash and cash equivalents at end of period 498.9 218.2